Dismounting the MDR horse.

نویسندگان

  • Edward Libby
  • Robert Hromas
چکیده

1. Lievens D, Zernecke A, Seijkens T, et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood. 2010;116(20):4317-4327. 2. Wei S, Kryczek I, Zou W. Regulatory T-cell compartmentalization and trafficking. Blood. 2006;108(2):426-431. 3. Ait-Oufella H, Salomon BL, Potteaux S, et al. Natural regulatory T cells control the development of atherosclerosis in mice. Nat Med. 2006;12(2):178-180. 4. Mor A, Planer D, Luboshits G, et al. Role of naturally occurring CD4 CD25 regulatory T cells in experimental atherosclerosis. Arterioscler Thromb Vasc Biol. 2007;27(4):893-900. 5. Moura R, Tjwa M, Vandervoort P, Van Kerckhoven S, Holvoet P, Hoylaerts MF. Thrombospondin-1 deficiency accelerates atherosclerotic plaque maturation in ApoE / mice. Circ Res. 2008;103(10):1181-1189. 6. Seijkens T, Engel D, Tjwa M, Lutgens E. The role of CD154 in haematopoietic development. Thromb Haemost. 2010;104(4). 7. Lutgens E, Gorelik L, Daemen MJ, et al. Requirement for CD154 in the progression of atherosclerosis. Nat Med. 1999;5(11):1313-1316. 8. Mach F, Schonbeck U, Sukhova GK, Atkinson E, Libby P. Reduction of atherosclerosis in mice by inhibition of CD40 signalling. Nature. 1998;394(6689):200-203. 9. Lutgens E, Lievens D, Beckers L, et al. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J Exp Med;207(2):391-404. 10. Leroyer AS, Rautou PE, Silvestre JS, et al. CD40 ligand microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis a potential mechanism for intraplaque neovascularization. J Am Coll Cardiol. 2008;52(16):1302-1311. 11. Huo Y, Schober A, Forlow SB, et al. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat Med. 2003;9(1): 61-67. 12. Dole VS, Bergmeier W, Mitchell HA, Eichenberger SC, Wagner DD. Activated platelets induce WeibelPalade-body secretion and leukocyte rolling in vivo: role of P-selectin. Blood. 2005;106(7):2334-2339. 13. Tjwa M, Bellido-Martin L, Lin Y, et al. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes. Blood. 2008; 111(8):4096-4105. 14. Ranke C, Hecker H, Creutzig A, Alexander K. Dosedependent effect of aspirin on carotid atherosclerosis. Circulation. 1993;87(6):1873-1879. 15. Andre P, Prasad KS, Denis CV, et al. CD40L stabilizes arterial thrombi by a beta3 integrin– dependent mechanism. Nat Med. 2002;8(3):247-252.

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عنوان ژورنال:
  • Blood

دوره 116 20  شماره 

صفحات  -

تاریخ انتشار 2010